Dyslipidemia in active juvenile dermatomyositis patients

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Dyslipidemia in active juvenile dermatomyositis patients

Methods 25 JDM patients followed at the Pediatric Rheumatology Unit of our tertiary University Hospital were compared to 25 healthy controls according to demographic data, fasting lipoproteins, glycemia and insulin, anti-LPL antibodies and muscle enzymes. All patients were evaluated by the same pediatric rheumatologist in order to evaluate the following JDM scores: Disease Activity Score (DAS),...

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Juvenile dermatomyositis.

Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...

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Juvenile dermatomyositis.

The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...

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Juvenile Dermatomyositis in Pregnancy

Juvenile dermatomyositis has variable clinical presentations both in and outside of pregnancy. A literature review indicated that optimal maternal and fetal outcomes can be anticipated when the pregnancy is undertaken while the disease is in remission. Poorer outcomes are associated with flare-up of the disease in early pregnancy compared with exacerbation in the second or third trimester, when...

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Juvenile dermatomyositis in Western Switzerland

Introduction Juvenile dermatomyositis (JDM) is a rare chronic, autoimmune vasculopathic disease with mainly muscle and skin involvement. The incidence described in USA is 2.5-4.1 cases per million children; the disease is slightly more common in girls. Recent studies describe that two third of the patients followed a chronic disease course, whereas only one third showed monocyclic disease course.

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2011

ISSN: 1546-0096

DOI: 10.1186/1546-0096-9-s1-p58